Squalene and Squalane
Expert Panel for Cosmetic Ingredient Safety
The Expert Panel for Cosmetic Ingredient Safety (Expert Panel) first reviewed the safety of squalene and squalane in 1982, concluding both were safe as cosmetic ingredients in what was then present practices of use and concentration.
The Expert Panel reviewed safety data and uses again in 2001 and 2019 reaffirming the original conclusion that squalane and squalene are safe as cosmetic ingredients in the present practices of use and concentration.
Squalane is listed on the EU’s Cosmetic Ingredient Inventory (CosIng) and may be used without restrictions in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union.
Squalene is listed in the EU’s Annex II, specifically under entry 419, which designates substances that are prohibited from use in cosmetic products.