Aluminum Zirconium Trichlorohydrex GLY
What Is It?
Aluminum Zirconium Trichlorohydrex GLY, Aluminum Zirconium Tetrachlorohydrex GLY, Aluminum Zirconium Pentachlorohydrex GLY and Aluminum Zirconium Octachlorohydrex GLY occur as a solids. These ingredients are complexes of Aluminum Zirconium Chlorohydrex (3, 4, 5 or 8 units) with glycine. These ingredients are used mainly in the formulation of personal cleanliness products.
Why Is It Used?
Aluminum Zirconium Trichlorohydrex GLY, Aluminum Zirconium Tetrachlorohydrex GLY, Aluminum Zirconium Pentachlorohydrex GLY, and Aluminum Zirconium Octachlorohydrex GLY are ingredients that are applied to the skin to reduce the production of perspiration at the site of application, to induce a tightening or tingling sensation of the skin and to reduce or eliminate unpleasant odor.
Aluminum Zirconium Trichlorohydrex GLY, Aluminum Zirconium Tetrachlorohydrex GLY, Aluminum Zirconium Pentachlorohydrex GLY, and Aluminum Zirconium Octachlorohydrex GLY are complexes of an inorganic and an A compound that contains carbon and hydrogen and usually other elements such as nitrogen, sulfur and oxygen.. GLY is an abbreviation for the Organic compounds that are the building blocks of proteins. glycine.
The Food and Drug Administration (FDA) has reviewed the safety of the Aluminum Zirconium Chlorohydrex GLY ingredients and has approved these ingredients for use as ingredients in Over-the-Counter (OTC) antiperspirant drug products. The Cosmetic Ingredient Review (CIR) was established in 1976 as an independent safety review program for cosmetic ingredients. The CIR Expert Panel consists of independent experts in dermatology, toxicology, pharmacolgy and veterinary medicine. The CIR includes participation by the U.S. Food & Drug Administration and the Consumer Federation of America. (CIR) has deferred evaluation of these ingredients because the safety has been assessed by FDA. This deferral of review is according to the provisions of the CIR Procedures.
More information about aluminum
More information about the safety of antiperspirant OTC drug products.
FDA Code of Federal Regulations for antiperspirant active ingredients including the Aluminum Zirconium Chlorohydrex complexes with glycine
In Europe, the uses of Aluminum Zirconium Chlorohydrate complexes with glycine are restricted to antiperspirant products according to the Cosmetics Directive of the European Union (see Appendix III).
In Canada, the use of zirconium compounds in cosmetics and personal care products, including the Aluminum Zirconium Chlorohydrex complexes with glycine, is regulated.
More Scientific Information
Aluminum Zirconium Chlorohydrex GLY compounds are coordination complexes of Aluminum Zirconium Chlorohydrate (3, 4, 5, or 8 units) and glycine in which some of the water molecules normally coordinated to the metal have been displaced by glycine.