Aluminum Zirconium Pentachlorohydrate
What Is It?
Aluminum Zirconium Trichlorohydrate, Aluminum Zirconium Tetrachlorohydrate, Aluminum Zirconium Pentachlorohydrate and Aluminum Zirconium Octachlorohydrate occur as solids. These ingredients are used in the formulation of personal cleanliness products.
Why Is It Used?
Aluminum Zirconium Trichlorohydrate, Aluminum Zirconium Tetrachlorohydrate, Aluminum Zirconium Pentachlorohydrate and Aluminum Zirconium Octachlorohydrate are ingredients that are applied to the skin to reduce the production of perspiration at the site of application, to induce a tightening or tingling sensation of the skin and to reduce or eliminate unpleasant odor.
Aluminum Zirconium Trichlorohydrate, Aluminum Zirconium Tetrachlorohydrate, Aluminum Zirconium Pentachlorohydrate and Aluminum Zirconium Octachlorohydrate are inorganic compounds.
The Food and Drug Administration (FDA) has reviewed the safety of Aluminum Zirconium Chlorohydrate complexes and has approved the use of these ingredients in Over-The-Counter (OTC) antiperspirant drug products. The The Cosmetic Ingredient Review (CIR) was established in 1976 as an independent safety review program for cosmetic ingredients. The CIR Expert Panel consists of independent experts in dermatology, toxicology, pharmacolgy and veterinary medicine. The CIR includes participation by the U.S. Food & Drug Administration and the Consumer Federation of America. (CIR) has deferred evaluation of these ingredients because the safety has been assessed by FDA. This deferral of review is according to the provisions of the CIR Procedures.
More information about aluminum.
More information about the safety of antiperspirant OTC drug products.
Link to FDA Code of Federal Regulations for antiperspirant active ingredients including the Aluminum Zirconium Chlorohydrate compounds
In Europe, the uses of Aluminum Zirconium Chlorohydrate complexes are restricted to antiperspirant products according to the Cosmetics Directive of the European Union. See Appendix III, Part 1.
Link to the EU Cosmetic Regulation:
In Canada, the use of zirconium compounds in cosmetics and personal care products, including the Aluminum Zirconium Chlorohydrate complexes, is regulated.
Please check the Health Canada website at http://www.hc-sc.gc.ca/cps-spc/person/cosmet/info-ind-prof/_hot-list-cri…
for updates and additional information about this list.
More Scientific Information
Aluminum Zirconium Chlorohydrates are complexes of basic aluminum chloride. The complexes are polymeric, loosely bound to water atoms, and depending on the complex, encompass a range of aluminum to zirconium ratios (from 2 to 10 aluminum atoms for each zirconium atom), and a range of aluminum to chloride ratios (2.1 to 0.9 total metal atoms to 1 chloride atom).
Find out more about the regulation of over-the-counter drugs by the Food and Drug Administration
OTC Drug Home Page: http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSa…
Information about OTC Drug monographs: https://www.fda.gov/drugs/over-counter-otc-drug-monograph-process
Search the Code of Federal Regulations http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm
EU Cosmetics Inventory http://ec.europa.eu/consumers/cosmetics/cosing/