What Is It?
Alpha-Isomethyl Ionone is a colorless or pale straw-colored liquid. In cosmetics and personal care products, Alpha-Isomethyl Ionone is used in the formulation of aftershave lotions, bath products, bubble baths, hair care products, moisturizers, perfumes and colognes, shampoos and skin care products.
Why Is It Used?
Alpha-Isomethyl Ionone is used as a Substances that impart an odor to a product..
Alpha-Isomethyl Ionone is a synthetic fragrance compound also known as 3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one, or cetone.
The Food and Drug Administration (FDA) has approved the use of Alpha-Isomethyl Ionone as a Ingredients that impart a flavor or a taste to a product. for direct addition to food. The safety of Alpha-Isomethyl Ionone has been evaluated by the Research Institute for Fragrance Materials Expert Panel (REXPAN). Based on this evaluation, an International Fragrance Association (IFRA) Standard has been established. The IFRA Standard restricts the use of mixed isomers of methyl ionone (including Alpha-Isomethyl Ionone) in fragrances because of potential sensitization.
Link to the IFRA Standards: http://www.ifraorg.org/en-us/standards_1
The The Cosmetic Ingredient Review (CIR) was established in 1976 as an independent safety review program for cosmetic ingredients. The CIR Expert Panel consists of independent experts in dermatology, toxicology, pharmacolgy and veterinary medicine. The CIR includes participation by the U.S. Food & Drug Administration and the Consumer Federation of America. (CIR) defers review of individual fragrance ingredients to the IFRA program unless the ingredient has significant uses other than as a fragrance. In this case, the ingredient may be assessed by both the CIR Expert Panel and REXPAN.
Link to FDA Code of Federal Regulations for Alpha-Isomethyl Ionone: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr…
The Joint FAO/WHO Expert Committee on Food Additives (JECFA) concluded that Alpha-Isomethyl Ionone does not present a safety concern at current levels of intake when used as a flavoring agent.
Link to the JECFA safety evaluation of Alpha-Isomethylionone: http://www.inchem.org/documents/jecfa/jeceval/jec_1204.htm
The Flavor and Extract Manufacturers Association Expert Panel has reviewed the safety of Alpha-Isomethyl Ionone and determined that it was Generally Recognized as Safe (GRAS) for use as a flavoring substance. In Europe, Alpha-Isomethyl Ionone is included on the list of “allergenic” substances.
The European Cosmetics Regulation requires manufacturers of cosmetics and personal care products to indicate the presence of certain “allergenic” substances in the list of ingredients if they are present above certain levels in the product (see Annex III). The presence of Alpha-Isomethyl Ionone must be indicated in the list of ingredients when its concentration exceeds: 0.001% in leave-on the skin products 0.01% in products that are rinsed off the skin.
Link to the EU Cosmetic Regulation: http://europa.eu/legislation_summaries/consumers/product_labelling_and_packaging/co0013_en.htm
More information about the safety of fragrances.
More Scientific Information
The odor of Alpha-Isomethyl Ionone has been described as woody, violet or floral.
Find out more about the regulation of Food Additives by the Food and Drug Administration
Food Ingredients and Packaging: http://www.fda.gov/Food/IngredientsPackagingLabeling/default.htm
Food Contact Substances: http://www.fda.gov/Food/IngredientsPackagingLabeling/PackagingFCS/default.htm
Substances Generally Recognized As Safe (“GRAS” is an acronym for the phrase Generally Recognized As Safe. Under sections 201(s) and 409 of the Federal Food, Drug, and Cosmetic Act (the Act), any substance that is intentionally added to food is a food additive, that is subject to premarket review and approval by FDA, unless the substance is generally recognized, among qualified experts, as having been adequately shown to be safe under the conditions of its intended use, or unless the use of the substance is otherwise excluded from the definition of a food additive.): http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/default.htm
Link to the Research Institute for Fragrance Materials: http://www.rifm.org
Search the FDA Code of Federal Regulations http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm
EU Cosmetics Inventory http://ec.europa.eu/consumers/cosmetics/cosing/