What Is It?

Cinoxate is a slightly yellow viscous liquid. Cinoxate is used in the formulation of sun protection products.

Why Is It Used?

Cinoxate, when applied to the skin, absorbs UV rays. UV radiation causes sunburn and is a significant cause of premature aging of the skin and contributes to the development of melanoma and other forms of skin cancer. Cinoxate can also be used to protect cosmetics and personal care products from deterioration by absorbing, UV rays

Scientific Facts

Cinoxate has the ability to convert incident ultraviolet radiation into less damaging infrared radiation (heat).

Safety Information

The Food and Drug Administration (FDA) reviewed the safety of Cinoxate and approved its use as an active ingredient in Over-the-Counter (OTC) sunscreen drug products at concentrations up to 3%. The Cosmetic Ingredient Review (CIR) Expert Panel has deferred evaluation of this ingredient because the safety has been assessed by FDA. This deferral of review is according to the provisions of the CIR Procedures.

Link to FDA Code of Federal Regulations for Cinoxate…

Cinoxate is not listed in Annex VII of the European Cosmetics Directive. Therefore, it may not be used in sunscreen products (products intended to protect the skin from the sun). If used to protect the product from UV radiation, Cinoxate may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union.

Link to the EU Cosmetic Regulation:…

Health Canada permits the use of Cinoxate in sunscreen products at a maximum concentration of 3%.

More Scientific Information

Cinoxate is an ester formed from methoxycinnamic acid and 2-ethoxyethanol. Cinoxate functions as a sunscreen agent and an ultraviolet light absorber.


Find out more about the regulation of over-the-counter drugs by the Food and Drug Administration

OTC Drug Home Page:…

Information about OTC Drug monographs:

Search the Code of Federal Regulations

EU Cosmetics Inventory