Expert Panel for Cosmetic Ingredient Safety:
The safety of pentylene glycol, 1,2-hexanediol and caprylyl glycol has been reviewed by the Expert Panel for Cosmetic Ingredient Safety. The Expert Panel reviewed the scientific data and concluded that these ingredients were safe as used in cosmetics and personal care products.
The Expert Panel reviewed data indicating that caprylyl glycol and the smaller compounds were easily absorbed into the skin. Additional studies suggested that these compounds are metabolized in the skin before they reach the systemic circulation. Repeated dose studies with these compounds have not resulted in significant adverse effects or effects on reproduction or development. These compounds were not genotoxic. Products containing the 1,2-glycol ingredients did not cause dermal irritation or sensitization.
Based on the data reviewed, the Expert Panel concluded that pentylene glycol, 1,2-hexanediol and caprylyl glycol are safe for use in cosmetic products.
Pentylene glycol, 1,2-hexanediol and caprylyl glycol may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union.