Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde

What Is It?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, also called HMPCC, is a clear, colorless liquid with a delicately sweet, light, floral odor. In cosmetics and personal care products, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde is used in the formulation of aftershave lotions, bath products, bubble baths, hair conditioners, moisturizers, perfumes and colognes, skin care products and suntan products.

Why Is It Used?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde functions as a fragrance ingredient.

Scientific Facts

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde is a synthetic fragrance compound.

Safety Information

The safety of Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde has been evaluated by the Research Institute for Fragrance Materials Expert Panel (REXPAN). Based on this evaluation, an International Fragrance Association (IFRA) Standard has been established. The IFRA Standard restricts the use of Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde in fragrances because of potential sensitization.

Link to the IFRA Standards: http://www.ifraorg.org/en-us/standards_1

The Cosmetic Ingredient Review (CIR) defers review of individual fragrance ingredients to the IFRA program unless the ingredient has significant uses other than as a fragrance. In this case, the ingredient may be assessed by both the CIR Expert Panel and REXPAN.

In Europe, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde is included on the list of “allergenic” substances. The European Cosmetics Directive requires manufacturers of cosmetics and personal care products to indicate the presence of certain “allergenic” substances in the list of ingredients if they are present above certain levels in the product (see Annex III). The presence of Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde must be indicated in the list of ingredients when its concentration exceeds: 0.001% in leave-on the skin products 0.01% in products that are rinsed off the skin.

Link to the EU Cosmetic Regulation: http://europa.eu/legislation_summaries/consumers/product_labelling_and_packaging/co0013_en.htm

More information about the safety of fragrances.

More Scientific Information

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, or HMPCC, is a mixture of two isomers. HMPCC has a soft delicate, floral, lily, cyclamen, and lilac note reminiscent of hydroxycitronellal.


Link to the Research Institute for Fragrance Materials: http://www.rifm.org

EU Cosmetics Inventory http://ec.europa.eu/consumers/cosmetics/cosing/