What Is It?

Aldioxa occurs as a white powder. In cosmetics and personal care products, Aldioxa was reported to be used in the formulation of eyeliners, eye shadows, mascaras, face powders and foundations.

Why Is It Used?

Aldioxa has been reported to function as a cosmetic astringent and a skin conditioning agent – miscellaneous.

Scientific Facts

Aldioxa is prepared from allantoin, a botanical extract of the comfrey plant, and aluminum hydroxide, to yield either a wet slurry or a dry blend.

Safety Information

The safety of Aldioxa has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that additional data were needed to support the safety of Aldioxa.

CIR Safety Review: All of the toxicologic parameters investigated in a 94-day subchronic feeding study with Aldioxa were similar in the test and the control group. No significant adverse results were obtained in a three generation study with 10% Aldioxa in the diet. A suspension containing 25% Aldioxa was not a sensitizer when applied to the back.

Intradermal injections of a 2% Aldioxa suspension on alternating days for a total of 10 applications with challenge after a 10-day nontreatment period also did not result in sensitization. A hydrophilic ointment containing 4% Aldioxa was neither an irritant nor a sensitizer when evaluated on 200 human volunteers. The CIR Expert Panel concluded that additional data, such as data on genotoxicity and phototoxicity were needed to complete the safety assessment of Aldioxa. Aldioxa may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union.

Link to the EU Cosmetic Regulation:…

More Scientific Information

Aldioxa is a heterocyclic organic compound. In cosmetics and personal care products, Aldioxa functions as an astringent and skin conditioning agent – miscellaneous.