The Food and Drug Administration (FDA) has approved Pyrophyllite as a color additive exempt from certification. Pyrophyllite is allowed to be used as a color in externally applied cosmetics and personal care products and drugs if it conforms to FDA specifications. It is not allowed to be used in products intended for the lips or the eye area.

The Food and Drug Administration (FDA) has reviewed the safety of Calcium Silicate and Bentonite and determined that they are Generally Recognized as Safe (GRAS) for use as direct food additives (Calcium Silicate at up to 2% of weight of food) and that Kaolin is GRAS for use as an indirect food additive. Aluminum Silicate is approved for use in polymers with incidental contact with food. Magnesium Aluminum Silicate (antacid), Magnesium Trisilicate (antacid), and Kaolin (skin protectant, anorectal) are used in Over-the-Counter (OTC) drug products.

The safety of Aluminum Silicate, Calcium Silicate, Magnesium Aluminum Silicate, Magnesium Silicate, Magnesium Trisilicate, Sodium Magnesium Silicate, Zirconium Silicate, Attapulgite, Bentonite, Fuller's Earth, Hectorite, Kaolin, Lithium Magnesium Silicate, Lithium Magnesium Sodium Silicate, Montmorillonite, Pyrophyllite and Zeolite has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that all seventeen ingredients were safe as used in cosmetics and personal care products.