Guanine
What is it?
Guanine is a crystalline material obtained from fish scales. In cosmetics and personal care products, Guanine is used in the formulation of bath products, cleansing products, fragrances, hair conditioners, lipsticks, nail products, shampoos and skin care products.
Safety Information
The Food and Drug Administration (FDA) lists Guanine as a color additive exempt from certification. It may be safely used in cosmetics, including those intended for use in the area of the eye, when it conforms to FDA specifications. Guanine may also be used in externally applied drugs, but not in oral drug products.
Cosmetic Ingredient Review (CIR) has deferred evaluation of this ingredient because the safety has been assessed by FDA. This deferral of review is according to the provisions of the CIR Procedures.
Cosmetic Ingredient Review (CIR) has deferred evaluation of this ingredient because the safety has been assessed by FDA. This deferral of review is according to the provisions of the CIR Procedures.
Why is it used in cosmetics and personal care products?
Guanine imparts a white color to cosmetics and personal care products. It also reduces the clear or transparent appearance of products and can be used in skin makeup for hiding blemishes.
Scientific facts:
Guanine used as a colorant is obtained from fish scales. It consists of two purines, Guanine and hypoxanthine. The Guanine content varies from 75 to 97% and the hypoxanthine content varies from 3 to 25% depending on the particular fish from which the crystals are derived. Guanine provides a pearly, iridescent effect when used in cosmetics and personal care products.








